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Seelig et al., 1984

Remaining at a low dose may improve tolerability for some patients, but it may not provide adequate glucose control for others

Visible weight loss often becomes more noticeable between 816 weeks

The introduction of an oral option is widely seen as a potential inflection point for obesity treatment, with experts noting it could broaden access and support wider uptake as the category continues to expand

[5, 6] It is considered the main redox buffer in human cells owing to its large amount of reducing equivalents, [7] and is an important enzyme cofactor that serves as a neuromodulator in the central nervous system