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Structural insights into ISRIB, a memory-enhancing inhibitor of the integrated stress response
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These hormones, known collectively as incretins, are secreted by the gut in response to nutrient ingestion and play crucial roles in metabolic regulation
30,109 Under nutrient excess, suppressed SIRT1 expression impairs autophagic activity, 96 leading to mitochondrial dysfunction and ROS accumulation, further disrupting insulin signaling
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