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Hernandez AF, Green JB, Janmohamed S, et al
#### Comparison summary table Side Effect Profile in Trials Reported side effects across all three compounds are dominated by gastrointestinal events [3][4][10]
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Semaglutide and tirzepatide have also been linked to pancreatitis, gallbladder disease and, more rarely, kidney injury tied to severe dehydration from gastrointestinal (GI) side effects
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