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Some participants in early studies experienced slight increases in heart rate or mild rhythm disturbances

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This figure is directly comparable to the performance of tirzepatide (Mounjaro) in the SURMOUNT-1 trial, which showed approximately 20.9% weight loss at 72 weeks, and exceeds the approximately 14.9% achieved by semaglutide alone in STEP 1

Kosowska A, Gallego-Colon E, Garczorz W, Kych-Ratuszny A, Aghdam MRF, Woz Niak M, et al