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2.1.3.7 Surgery recapitulates metabolic syndromes There are parallels between the immune metabolic changes in surgery and those in other conditions for instance, the cytokine storm and subsequent immune exhaustion in severe COVID-19 or sepsis have similar roots in mtDAMPs release and metabolic collapse

Koyanagi and S

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Senescent chondrocytes accumulate in osteoarthritic joints, contributing to inflammation and tissue breakdown via the senescence-associated secretory phenotype (SASP)

Step 3 Medical Intake Vitals, medical history review, questions answered