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Proc Natl Acad Sci U S A 95(13):78057812 Reed MC, Nijhout HF, Neuhouser ML, Gregory JF, Shane B, James SJ, Boynton A, Ulrich CM (2006) A mathematical model gives insights into nutritional and genetic aspects of folate-mediated one-carbon metabolism
In rested, well-nourished healthy adults, most trials find either no measurable benefit or a small one on specific tasks
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While there are no absolute dietary restrictions, certain dietary approaches may help minimize side effects
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