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Some patients may remain on 1.7 mg if the 2.4 mg dose is not tolerated
But what was striking is the challenge, and this is one of the first important questions about, when you had the extended half-life of the first GLP-1 drug, that instead of having to take multiple times a day, you could actually, with liraglutide get to a point where you were starting to get to an extended half-life
Furthermore, semaglutides gastrointestinal side effects, though generally manageable, could pose challenges for some patients, potentially impacting adherence to both semaglutide and hormone therapies
This altered absorption pattern is why some people report feeling intoxicated faster or experiencing effects that last longer than before starting therapy
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