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10.1016/j.ejmech.2015.04.040 122 PolingJ
Agents who monitor these changes and build relationships with new market entrants often find themselves ahead of the competition when enrollment periods open
Since then, several clinical studies have shown its safe and effective use - but the pharmacuetical companies have decided not to (yet) pursue FDA-Approval (likely because each new FDA-Approval costs several million dollars to go through the process, and because there are a good deal of drugs used off-label in the way tranexamic acid is for melasma, especially when the drug has a long history of safety and efficacy, as is in this case)
Larson K, Yan S-J, Tsurumi A et al (2012) Heterochromatin formation promotes longevity and represses ribosomal RNA synthesis
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