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For example, the weekly injections Wegovy and Mounjaro, which are brand names for semaglutide and tirzepatide, respectively

When semaglutide binds to these receptors, it triggers intracellular signaling cascades that increase cyclic adenosine monophosphate (cAMP) levels, ultimately modulating cellular function in a tissue-specific manner

Both treatments were safe with benign safety profiles

Topical effects Most reported topical effects are mild and local: redness, tingling, dryness, or transient irritation at the application site, typically more common with concentrations above 4%

"The better question is: Which treatment is actually medically appropriate?" Below, experts break down how Ozempic and Wegovy compare, who qualifies for each and what to know before talking to your doctor