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In summary, semaglutide induced modest weight loss in leptin-deficient ob/ob mice but produced marked sexual dimorphism in tissue remodeling
10.1249/01.MSS.0000139795.83030.D1 159 WolfeR.FerrandoA.Sheffield-MooreM.UrbanR
If you were worried use your judgement about anesthetic management #3 In this trial, we found that adults with obesity (or overweight with one or more weight-related coexisting conditions) and without diabetes had a mean weight loss of 14.9% from baseline with semaglutide as an adjunct to lifestyle intervention
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