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Clinical data confirms that injection site reactions are most often transient and generally diminish as the body adjusts to the medication over 4 to 8 weeks

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Needles should be 0.5 inches in length maximum to prevent accidental intramuscular injection, which alters the absorption kinetics designed for subcutaneous depots and can cause increased side effect intensity

GLP-1 also attenuates small bowel motility, enhancing time for enzymatic nutrient digestion and absorption