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Doctors are saying, Okay, well, take your GLP-1s and this is going to make you less motivated for food, but we somehow expect you to have more motivation to change your diet and to exercise. If its gonna dampen your desire to kind of eat, isnt it also going to dampen your desire, like that high you get from working out, or that [thought], Hey, I wanna be healthier, maybe I should go for a salad. If you think the only reason to eat better is to lose weight and something else is making you lose weight, that might actually give you inherently less motivation to eat better.
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In summary, FOXO4 plays a critical role in multiple diseases, and studies have shown that endothelial cell senescence accompanies these conditions
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