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It is also used off-label for prediabetes and polycystic ovary syndrome

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doi: 10.1016/j.bpj.2010.07.063 96

51 Park et al 52 found that empagliflozin, dulaglutide and a combination of both significantly attenuated the increase in cells, especially macrophages and neutrophils, in airway alveolar lavage fluid induced by a high-fat diet in mice, reduced the expression of IL-17 and transforming growth factor (TGF)-1, and decreased the differentiation of Th cells to Th1 and Th17, thereby achieving a reduced inflammatory response

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