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A practical refeed approach involves one day per week where calories increase by 20 to 30% above your typical intake, with most of the increase coming from carbohydrates rather than fats

Acknowledgements We would like to thank Jatinder Dhillon and the MedImmune Biologics Expression and Early Expression and Supply teams for generating the peptide-antibody fusions, Sarah Will and Arthur Suckow (MedImmune LLC, Gaithersburg, MD, USA), Dominic Corkill (MedImmune Ltd, Cambridge, UK), Michael Feigh (Gubra, Horsholm, Denmark), the MedImmune and AstraZeneca in vivo science teams for assistance in the design and conduct of rodent studies, Joerg Bluemel (MedImmune LLC, Gaithersburg, MD, USA) for supervising the non-human primate study as well as Nicholas Bhagroo (MedImmune LLC, Gaithersburg, MD, USA) for performing the in vitro glucose-stimulated insulin secretion assay

Lenzi A, Lombardo F, Gandini L, Culasso F, Dondero F