AAS exposure has been associated with prolongation of ventricular repolarisation, increased dispersion of action potential duration, and reduced heart-rate variability, all of which facilitate arrhythmogenesis (71)
doi: 10.1016/j.ejps.2006.04.016, 123
SCFAs mainly include acetate, propionate, and butyrate, which are produced in the gut in different proportions: acetate (60%), propionate (25%), and butyrate (15%) [181, 182]
As a result, glutathione is an important part of the body's natural defense mechanisms and maintaining these levels is essential for a healthy life
We utilized natural tyrosinase inhibitors reported in the literature for molecular docking and molecular dynamic simulations to examine their binding modes with mTYR and hTYR