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In lipopolysaccharide primed macrophages, capsaicin induced TRPV1 activation and Ca 2+ influx promote polarization toward an M2 macrophage phenotype characterized by anti-inflammatory properties, thereby improving the adipose tissue inflammatory microenvironment and attenuating insulin resistance (63)
Moreover, the translational applicability of our results is constrained by the models preventive characteristics
Med Res Rev
The amplified fragment from gr knockout mutant using primer pairs gr OF/ gr OR was sequenced to confirm the mutants
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