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the design is intended to extend half-life and reduce the amyloid-aggregation tendency of native human amylin while retaining amylin-receptor agonist activity
Previous studies reported that the administration of the GLP-1R agonist exendin-4 (25 nmol/kg, twice daily) inhibits learning and memory formation through the suppression of synaptic plasticity in the hippocampus of a high fat diet mouse model (Gault et al., 2010
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Decreased DSIP Levels in Depression: Implications for Therapy
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