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3.3 Metabolic modulation and immunomodulatory effects The close relationship between BMI, metabolic dysfunction, and immune activation has important implications for the potential use of GLP-1Ras in obese patients with PsA

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The fat returns toward baseline if you stop, so results depend on continued treatment

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What can we conclude To date, we have not seen robust reports that persons with obesity or overweight taking GLP-1 medications experience greater SMM loss than persons with obesity or overweight taking non-GLP-1 medications (after controlling for greater total weight loss)

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