Intriguingly, arginine-mediated inhibition of autophagy promotes breast tumor cells death in the presence of inhibitors of heat shock protein 70 (a stress-response protein involved in the adaptation to proteostasis) [93]
17,18 In addition, in some cell types, NADPH binds to the important H 2 O 2 -disposing enzyme: catalase, and reactivates it when it has been inactivated by H 2 O 2
TET2 negatively regulates nestin expression in human melanoma
10.1016/S0887-8994(97)00026-X Matsumoto J, Ogawa H, Maeyama R, Okudaira K, Shinka T, Kuhara T, Matsumoto I: Successful treatment by direct hemop-erfusion of coma possibly resulting from mitochondrial dysfunction in acute valproate intoxication
Familial IPF accounts for less than 5% of the total of patients with IPF and is clinically and histologically indistinguishable from sporadic IPF