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It should be based on: Long-term results Long-term safety Long-term affordability Long-term quality of life That is exactly why gastric sleeve remains such an important option, even in the GLP-1 era
CVOTs primarily proved cardiovascular safety and tolerability of different GLP-1 receptor agonists, but also showed cardiovascular benefit of specific drugs
Schmidt had joined what we might call the great American GLP-1 experiment
In that moment, I decided I'd give compounded semaglutide a try, and if anything unbearable happened (like super nasty side effects), I could at least say I tried and cross that one off my list
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