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The review also documented how GCL expression is transcriptionally upregulated by electrophiles through antioxidant response elements (ARE/EpRE) in the GCLC and GCLM promoters establishing the Nrf2/ARE pathway as the master regulator of GSH biosynthetic capacity under stress conditions
J Neurol Neurosurg Psychiatry 65 : 446453
It balances important bodily functions like blood production, cell division, and protein creation
Microalgae: a potential alternative to health supplementation for humans
Conclusion: Glutathione is safe, tolerable and effective whitening agent when used in topical cream (2%) and also in oral form in treatment of melasma.
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