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1 Introduction Obesity is a progressing and chronic condition defined by Body Mass Index (BMI) over 30 Kg/m2 levels

Dulaglutide Dulaglutide is another GLP- 1 synthetic analog which consists of two DPP- 4 resistant GLP- 1 molecules that are covalently linked to a modified IgG4 Fc fragment that acts as carrier, limiting the renal clearance of the molecule [93]

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SIRT6 mitigated diabetic HFpEF (48), SIRT5 improved fatty acid metabolism through CPT2 desuccinylation in diabetic cardiomyopathy (45)

8.Weight Gain in Women at Midlife: A Concise Review of the Pathophysiology and Strategies for Management.Mayo Clinic Proceedings