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What are the consequences of low glutathione levels

The present findings are in line with previous evidence suggesting that metabolic alterations are not uniformly associated with all clinical manifestation of depression, but map more consistently with specific symptom profiles [51]

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Mechanistic studies reveal that SFN significantly downregulates programmed death-ligand 1 (PD-L1) expression on tumor cells through multiple mechanisms, including direct covalent modification of cysteine residues on STAT1, which inhibits its transcriptional activity and blocks IFN--induced PD-L1 expression (75)

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