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Figure 4 LECs rapidly upregulate the expression of pro-inflammatory cytokines in response to lens manipulations/injury or cataract surgery Cataract surgery induces a phenotypic change in the retained peripheral LECs, which leads to their proliferation, migration, and differentiation into the myofibroblasts and dysgenic lens fibers that contribute to Soemmerings ring, and PCO (89, 186)

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