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This causes an increase in muscle mass and strength, as well as fat loss due to increased metabolism and lipolysis (the breakdown of fat)

They may also lead to hypoglycemia (low blood sugar), especially in people who take other anti-diabetes medicines

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Given the role of NADPH in the process of phagocytic killing it should be clear that individuals with reduced ability to produce NADPH (such as those with G6PD deficiencies) may also manifest with symptoms that have similarities to those of classically inherited forms of CGD

The combination of these two drugs aims to leverage their complementary mechanisms, maximizing weight loss and metabolic control