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Water content in lyophilized peptides is typically below 5%, and at this moisture level, hydrolysis (the primary degradation pathway for peptides) proceeds at a negligible rate

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Metabolic Changes and Loss of Insulating Body Fat Rapid fat loss removes insulation that normally traps body heat

The chemical structure of Tirzepatide has a peptide backbone with a fatty acid side chain to improve its half-life and duration of action in the body