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Historically, this increased insulin response mediated by GLP-1 and GIP had been attributed to factors termed incretins (derived from incretion, a term used at that time to refer to a secretion that remains inside the body), hence the name incretin effect is still used today to describe the rise in insulin mediated by the action of these hormones
The session also explored the expanding footprint of GLP-1 drugs, which have disrupted both therapeutic and commercial landscapes
If weight loss is a primary goal alongside diabetes management, Ozempic delivers significantly better results
Its unclear exactly when retatrutide will be FDA approved, but it is currently in late-stage clinical trials
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