tirzepatide icer Reduces Food Intake and Appetite, and Affects Brain Functioning, more than a Placebo and Liraglutide Mounjaro (tirzepatide) for the Treatment

Gastrointestinal side effects include: Nausea (15-30% of patients depending on dose): Usually mild to moderate and decreasing over time Diarrhea (13-24%): May contribute to dehydration if persistent Vomiting (6-12%): More common at higher doses Constipation (5-17%): Can alternate with diarrhea in some patients Abdominal pain (6-10%): Typically mild and self-limiting Decreased appetite : An intended effect contributing to weight loss Hypoglycemia risk varies depending on concurrent medications

A role for beta-cell-expressed G protein-coupled receptor 119 in glycemic control by enhancing glucose-dependent insulin release

But "slightly" is the operative word

10.3892/ol.2014.2358 15

This underscores the importance of barrier repair as a therapeutic strategy independent of anti-inflammatory effects