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Those who have successfully implemented sustainable changesincluding regular physical activity (UK Chief Medical Officers recommend at least 150 minutes of moderate-intensity activity weekly), improved dietary patterns, and behavioural strategies for weight managementmay have better outcomes if discontinuing GLP-1 therapy

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Long-acting versions like semaglutide and liraglutide are particularly effective, showing significant reductions in blood sugar levels and weight

Armstrong, 1997

However, a Guardian investigation previously found some online pharmacies either breaking these rules outright, or exploiting grey areas to peddle the medications to the public