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Genetic variation in GLP1R (the semaglutide receptor gene), GIPR (glucose-dependent insulinotropic polypeptide receptor), and metabolic genes like FTO and MC4R influence individual response to GLP-1 therapy
For many individuals, these effects attenuate over time as physiological adaptation occurs, though some patients continue to experience persistent symptoms throughout treatment
Although several psychological factors (for example, deficit in impulse control) are known to play a major role in the pathophysiology of obesity 248 , we here raise the issue of disparity in the provision of psychiatric care for the treatment of obesity compared with other eating disorders, which are predominantly treated by psychiatrists, and advocate for the importance of a multidisciplinary, integrated approach to weight management
And I said, you know, like, what about magnesium
Most patients can begin treatment the same day after an in-person consultation
