In research models where caloric intake is unrestricted, this is typically well-tolerated
The hallmark symptom of gallstones is biliary colic , typically presenting as: Sudden-onset pain in the right upper quadrant or epigastrium (upper central abdomen), often described as severe, constant, or cramping Pain radiating to the right shoulder or between the shoulder blades Episodes lasting 30 minutes to several hours , often triggered by fatty meals Associated nausea and vomiting Pain that may wake the patient from sleep When a gallstone obstructs the cystic duct or common bile duct, or when the gallbladder becomes inflamed, more serious complications can develop
It holds water in the intestinal lumen, counteracting the increased water absorption that comes with extended transit time
Vukojevic et al., 2018) as well as hyperkalemia-induced hypertension (Stupnisek et al., 2015)
After Wednesday, April 15 , selfpay patients will pay $199 per month for 4mg doses