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In the context of alcoholism, chronic acetaminophen ingestion can cause toxicity at doses that are generally safe (alcohol-tylenol syndrome)
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Elevated BDNF activates the TrkB receptor pathway, which triggers anti-apoptotic signaling cascades
(PMID: 34827486) and the broader systematic review by Ho and Nation (PMID: 29733881) provide some supporting evidence from outside the affected research group
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