In September 2022, Eli Lilly published the results of its preclinical studies on LY3437943 in the journal Cell Metabolism, in an article titled "LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept." In vitro and in vivo validation of the triple agonist effect of LY3437943: Eli Lilly's research results show that LY3437943 demonstrates superior weight loss effects compared to GLP-1 receptor (GLP-1R) selective agonists (GLP-1 RA), GLP-1R and GCGR dual agonists (Cotadutide or 05677), and GLP-1R and GIPR dual agonists
While this research suggests that drugs like Ozempic and Wegovy do appear to be effective when it comes to shedding a few extra pounds in the short term, what effect can they have over a longer period of time
Mechanism of action: Both drugs fall into the class of medications known as GLP-1 receptor agonists that enhance insulin secretion, suppress glucagon release, and slow gastric emptying to help control blood sugar levels
Science Day helps to establish facts and relationships between the drugs, current research and the plaintiffs claims
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