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Coffee polyphenols can change genes involved in glutathione synthesis
It appeared that sulofenur can undergo metabolic biotransformation to yield the GSH-conjugate of p -chlorophenyl isocyanate [ S -( N - p -chlorophenylcarbamoyl) GSH, SCPG
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FIGURE 3 The pharmacokinetic (PK) profile of GL is highly dependent on the route of administration, with marked differences between oral and intravenous delivery due to its unique metabolic pathways and transporter-mediated disposition
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