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Inject subcutaneously in the lower back region, 1 to 2 inches away from the spine itself

doi: 10.1016/j.clinthera.2017.11.011 41 KuhnCWeinerHL

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This anion then quickly breaks a disulfide bond and leads to Cys 63 nucleophilically attacking the nearest sulfide unit in the GSSG molecule (promoted by His 467 ) thus creating a mixed disulfide bond (GS-Cys 58 ) and a GS - anion

However, this is based on subgroup analysis (which has less statistical power than the overall finding), so it should be interpreted with appropriate caution