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Most resolve with stool softeners, fiber, sitz baths, and over-the-counter hydrocortisone within 2 to 4 weeks
To investigate further, this study presented the BPC-157 peptide in amphetamine (dopamine agonist) murine models
We also know that the lowest effective doses in the studies we've seen are 300mg of goat's rue, 600mg of shatavari, 600mg of fennel seed, and 2g of anise, and milk thistle studies have seen positive effects in doses as low as 420mg
This additional efficacy is attributed to GIP receptor activation, though the precise mechanisms remain under investigation
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