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The mechanism underlying these gastrointestinal cytoprotection-associated findings has been attributed in published research to NO-related maintenance of mucosal microvascular function and preservation of endothelial integrity, rather than to simple acid suppression

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Riboflavin is a precursor of flavin adenine dinucleotide (FAD), a coenzyme required for the activity of the folate-metabolizing enzyme, 5,10-methylenetetrahydrofolate reductase (MTHFR)

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