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They also achieved at least a 5% or 10% weight loss, which was significant
Therefore, while aware that the pharmacological modulation of the NRF2/ARE pathway could undeniably offer new therapeutic opportunities for diseases related to OS, we should at the same time consider that most of the currently known activators of NRF2 are not particularly specific, leading to an increased risk of off target toxic effects
ISSN 1552-4469
Acknowledgements We would like to thank BioRender for providing drawing support
It is also the first in-depth investigation of what the researchers call GLP-1 resistance
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