This is legal practice in the US, but Ozempic is not FDA-approved for obesity
To test whether increased senescence in immune cells from the kidney marrow contributed to the cellular activation in young versus aged killifish, we treated cells from young and aged killifish with a senolytic (fisetin) before immune cell stimulation using LPS
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"Obesity is a chronic disease, and people living with obesity deserve treatment options that match the complex biology of their neurometabolic disease," said Ania Jastreboff, M.D., Ph.D., Professor of Medicine & Pediatrics (Endocrinology) at the Yale School of Medicine, Director of the Yale Obesity Research Center (Y-Weight), and lead investigator