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The choice of B12 formulation should be guided by the individual patients needs and clinical presentation. Expert Consensus on B12 Therapy In summary, knowing the different B12 formulations and their dosing is key for managing B12 deficiency

What is Vitamin B-12

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The key difference comes down to bioavailability, which is how much of a nutrient your body can actually absorb and use

Vitamin B12, Fact Sheet for Health Professionals, National Institutes of Health, Office of Dietary Supplements Common questions about hydroxocobalamin, NHS (National Health Service), Hunt A, Harrington D, Robinson S