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was supported by Japan Society for the Promotion of Science (18H02621

The trials used daily supplementation without interruption for 12 months minimum, with the four-year follow-up showing continued improvement

In this review, we summarize the latest research on the etiology, pathogenesis, diagnosis, prevention, mechanism, and pharmacological and nonpharmacological treatment of MDD as well as related clinical experiments

This activation enhances cell migration and survival at injury sites, enabling cells to move into damaged areas and initiate tissue rebuilding