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GLP-1 receptor agonists in stroke prevention: a narrative review on emerging therapeutic frontiers
The science is intriguing but low bioavailability has led the company to pursue very high doses
(December 2019)
Absolute contraindications Medullary thyroid cancer MEN-2 Pregnancy or breastfeeding Prior severe allergic reaction to GLP-1 medications Conditions requiring extra caution Gastroparesis or delayed gastric emptying History of pancreatitis Advanced diabetic retinopathy Use alongside medications that increase hypoglycemia risk These and a few other situations require individualized assessment, which is why specialty endocrine care matters
Lurie R, Ben-Amitai D, Laron Z: Laron syndrome (primary growth hormone insensitivity): a unique model to explore the effect of insulin-like growth factor 1 deficiency on human hair
