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In fact, impaired GSH synthesis or reduced GSH import into the periplasm is connected to several phenotypes, similar to those found in cells lacking the DsbA/DsbB- or DsbC-system (Fabianek et al., 2000

The WNK kinases are responsible for modifying transporter activity in response to varying physiological demands

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549,550,551,552,553 Single-cell RNA sequencing revealed a significant reduction in astrocytes in AD mice, with ferroptosis activated in astrocytes, and FTH1 in astrocytes was identified as a hub gene associated with ferroptosis