While these GLP-1 medications can mute those obesity-promoting pathways or heighten obesity-fighting pathways, those pathways, fundamentally, still exist, Maselli says
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These medications work by mimicking the action of the naturally occurring GLP-1 hormone, which stimulates insulin secretion in response to food intake, suppresses glucagon release, slows gastric emptying, and reduces appetite
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Alternatively, obesity may also promote cholesterol metabolism toward the production of bile acids with the aim of facilitating the absorption of excess body fat [47], in line with our findings