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We did, however, observe a 5.4 mmol/mol (0.5%) reduction in HbA 1c in the GLP-1 RA cohort, similar to reports from randomised controlled trials [45, 46]

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The Medicines and Healthcare products Regulatory Agency (MHRA) has approved these medications following rigorous clinical trials demonstrating their efficacy in glycaemic control, with some agents (liraglutide, dulaglutide, and semaglutide) also showing cardiovascular benefits in specific populations