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Specifically, Asp 21P forms a salt bridge with R242 ECL1 , while Trp 25P forms a hydrogen bond with D244 ECL1 and pi-pi stacking with W249 ECL1 , which was stabilized by Phe 22P
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19 Apparently, the Lys 27 and Asn 28 of exenatide play important roles in binding with the receptor
Consumers are struggling to afford brand-name GLP-1 drugs, and the less expensive compounded versions are expected to soon be phased out
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