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In fact, in an analogous class B receptor, the parathyroid hormone receptor-1 (PTH1R), the ECD can adopt more than one conformation while bound to a long-acting PTH analog and in the Gs-coupled state 5

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Cryo-sections of calf muscle (mid-belly portion, 15-m thickness) were blocked with sterile donkey serum/BSA/gelatin solution prior to incubation with HiLyte Fluor 647-labeled anti-nitroY198-HGF mAb (clone 3A11C6

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