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Globally, obesity rates are accelerating significantly, compelling the healthcare professionals to prescribe these drugs mainly for their certified efficacy in facilitating weight loss, particularly in diabetic patients
Mutat Res 625:2028
Eventually, this results in chronically insufficient GSH levels to neutralize the ROS, leading to oxidative stress that damages lens proteins
Pros of GLP-1s: Non-surgical option Can lead to 1520% body weight loss in clinical trials May improve blood sugar, cholesterol, and inflammation Weekly injections, often self-administered Cons of GLP-1s: Real-world weight loss may be lower than clinical trials (510%) Side effects include nausea, vomiting, fatigue, and gastroparesis High cost and limited insurance coverage Weight may return if medication is stopped What is weight loss surgery
Nelson, D
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