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In addition to residual cardiovascular risk despite aggressive LDL reduction, high costs limiting accessibility, and unresolved long-term safety concerns, past failures of HDL-directed therapies such as CETP inhibitors underscore the complexity of lipid biology
As the population of older adults grows and the wider clinical acceptance of therapies increases, the adoption rate is speeding up
Approximately 66 million adults in Europe currently live with diabetes, representing a substantial patient population for GLP-1 therapies
The truth is more nuanced: GLP-1 medications can be part of a long-term care plan, but ongoing success depends on understanding how appetite, metabolism, and daily habits work together
They have evolved from simple diabetes treatments into powerful, multi-faceted therapies that can protect the heart, kidneys, and liver, while also addressing a range of other health concerns
