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Extra caution is appropriate in patients with active cancer, recent cancer, unexplained masses, unexplained weight loss, pregnancy, breastfeeding, known allergy to peptide products, active infection, immune compromise, significant liver or kidney disease, active inflammatory or autoimmune disease flares, unusual clotting history, uncontrolled cardiovascular disease, use of chemotherapy or immune-modifying biologic therapy, and competitive athletes subject to anti-doping rules

NAC significantly reduced markers like morning stiffness, disease activity score, nitric oxide, fasting blood sugar, and increased HDL cholesterol, although not all improvements were significantly different from the placebo group

Putignano P, Dubini A, Toja P, Invitti C, Bonfanti S, Redaelli G, et al

Our group have recently demonstrated the anti-epileptic effects of XNJ in several acute mice models, including MES, PTZ, and KA models, but the overall effect was not as good as VPA (200 mg/kg) [116]

doi: 10.1002/kjm2.12226 181 ZhangMXueSJYangFXiaoMTangYBWuY